They don't. Think your college professor didn't care about you? Your co-workers care even less. They don't care about your weekend, your well-being, or your personal life. Some of them won't even care enough to say "how are you" when you see them in the morning. Unlike your classmates in college, your officemates in the real world don't want to get to know you! They want to finish their work and get the fuck out of the office as soon as possible.
You are
just a number to them.
Welcome to corporate America, kid.